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Welcome to Ray Tile Bathroom Remodeling, a company that specializes in all things bathroom remodeling in Piscataway Township, NJ and the surrounding areas. If you are looking for an easy and affordable way to transform your bathrooms, then our professional team of bathroom remodelers at Ray Tile Bathroom Remodeling is here to help you.
Bathroom remodeling is a costly home improvement project. Between expensive cabinetry and intricate plumbing work, it only makes sense that homeowners seek to save money in other areas such as retiling. However, this approach might lead to unsatisfactory bathroom features that dont look or perform the way you want!
We can help with all aspects of your bathroom renovations including vanity installation, tile installation, faucet installation, shower installation, shower pan installation, and everything in between. With our ceramic tiling and ceramic repair help, you can ensure your bathroom gets the proper finishing you've always dreamed of. Our attention to detail is unmatched and we'll make every aspect of your bathroom looking its best.
With over 13 years of experience, our goal is to provide a professional service that exceeds our clients' expectations. Our bathroom remodeling company seeks to be better than our competition by having flexible hours and carefully listening to our customers' needs. All of our bathroom remodeling contractors are equipped with the latest technology and equipment, so our team is ready to tackle on any complexity of work quickly and efficiently. Whether you need us, just know that we are here on standby ready to help.
Ray Tile Bathroom Remodeling offers professional tile Installation services by employing the right equipment and personnel to complete a job in an efficient manner. Our core objective is to achieve the highest level of customer satisfaction by providing quality workmanship. If you are interested in any of our bathroom remodeling services, go ahead and contact Ray Tile Bathroom Remodeling today for a free estimate.
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Ray Tile Bathroom Remodeling is a Bathroom Remodeling ...
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Energy efficient windows with lifetime warranties provide peace of mind and energy savings. We carry every type of window and many grid, color and other options to choose from.
Your home's siding protects against the elements and defines the look of your home. Change the look and feel of your house while simultaneously eliminating painting with new vinyl siding.
As a Certified GAF contractor you can rest assured that our complete roofing systems featuring GAF Timberline shingles and all the necessary components won't leak.
Whether its a complicated front door unit with sidelights and transom or a basic backdoor, our entry doors will eliminate drafts and maintenance and add great style to your house.
Sliding doors for decks and patios that open easily and seal your house from the elements. A range of options are available including colors, blinds and multi-point locking systems.
Garage Doors built to last with heavy duty tracks and rollers and extended warranties. A range of panel styles with multiple color and window options let you choose the perfect design.
Retractable, fixed fabric or aluminum awnings that shade you from the sun and protect from precipitation with literally hundreds of color options.
Powder coated aluminum railings that wont rust or virtually maintenance free vinyl railings enhance safety and aesthetics. Available with various designs and colors.
Resurface your existing deck with new wood or composite decking that is stain and fade proof.
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NJ Windows, Siding, Roofing, Entry Doors, Garage Doors ...
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Luxury Home Remodeling Dallas and Custom Home Builder DFW
Joseph & Berry is a general contracting and design-build firm specializing in Dallass exclusive private residential market. We cater to a select group of clients, working with top-notch designers and architects to deliver excellence on each project.
As a nationally recognized home remodeling contractor and custom home builder, we provide a WHITE GLOVE customer experience that makes the entire design-build process as seamless and stress-free as possible for our customers satisfaction.
Joseph & Berry specializes in high-end large whole house remodeling projects, high rises, and kitchen & bath remodeling in Dallas.
OUR MISSION
To provide a white glove construction experience
Home Builders In DFW
A custom home is a perfect solution for people who already have a vision of the home they want, and dont want to spend months to years searching for the perfect house.
While remodeling an existing home will hold some structural and design limitations, a new custom home allows you to shape every space and feature to fit your familys specific needs. Using state-of-the-art technologies and energy-efficient applications, we build our homes to last.
Joseph & Berrys team will guide you step by step through the home building process, from our first design meeting, all the way until your first family dinner in your new home.
If you are looking for custom home builders in DFW, you got to the right place.
Home Remodeling Dallas
Whole house remodeling projects can be stressful and can lead to so many questions. Can I live in my house while the work is being done? How long will a remodel take? How much will it cost? Am I ready for this? Joseph & Berrys unique white-glove customer service experience, stress-free process, and clear communication will help you minimize those types of concerns and answer all of your questions regarding your next home remodeling Dallas Tx project. Our talented team will help you turn your home renovation in Dallas dreams into a reality.
While you are still looking for the best construction company in Dallas, Tx to perform your home remodeling, we are thrilled to share that Joseph & Berry won the prestigious national award; Best In America Living (known as BALA) by National Association of Home Builders. Joseph & Berry has been recently named as the best remodeling company in united state by NKBA association and their Kitchen & Bath magazine.
If you consider renovating your home in the historic district in Dallas, we are happy to offer our expertise and knowledge on this process as one of the best remodelers in Dallas. Well be glad to learn more about your Dallas home remodeling project, submit the contact form and well contact you soon!
KITCHEN REMODELING
Your kitchen today is not just a place to cook anymore. Your kitchen today defines your lifestyle. A great kitchen will gather all your family and friends around it while helping you make the most out of your cooking skills. At Joseph & Berry, we understand this major function of the kitchen in your life, and our amazing kitchen designers will help you to create the best space that fits your unique family needs.
We specialize in reconfiguring any old kitchen into a dream luxuries kitchen retreat. No matter if youre completely redesigning your kitchen from light fixtures and flooring to countertops and cabinets or need to create a whole new space for your kitchen, Joseph & Berry has you covered for your next kitchen remodeling Dallas. From your first design consultation until the last step in the construction process, your dedicated Joseph & Berry team will be with you every step of the way. See why so many Dallas area homeowners have trusted us with their kitchen remodeling Dallas Tx.
Joseph & Berry has named as the best kitchen renovation company and kitchen remodel design in Dallas Tx by the Architect magazine click here to see why: Architect Magazine
BATHROOM REMODELING
Joseph & Berry specializes in luxury bathrooms renovation forthe park cities and Dallas homes. We love to create relaxing spaces for you to start or finish your day in.
Ourbathroom remodeling services go beyond just replacing an old bathtub or slapping in some new cabinets. Our award-winning designers work hand-in-hand with each customer to review inspiration boards, sample projects and design options to help create the perfect vision of your new bathroom. Only after youre completely satisfied with the direction of the project, will our bathroom construction team come out to your home and bring the vision to life. Whether if you wish for a bathroom remodel or a whole house renovation, you cam to the right place.
Our bathroom remodeling projects has named year after year, as the best bathrooms in Dallas Tx by NARI and the Dallas builder association.
What makes Joseph & Berrys experience different?
We dont just call ourselves a luxury home remodeling company without a way to back up our claims. In the same way that brands like Nordstrom and Ritz Carlton create an unparalleled, deluxe experience for each and every customer at Joseph & Berry, we aim to ensure that every communication and interaction is as pleasurable as possible, contributing to a memorable experience.
1.White glove customer serviceWe design our company culture to serve a busy and fast-paced lifestyle. You can keep focusing on your busy career and your precious family, while we will take care of your home. Our goal is to create a stress-free environment during the remodeling process while providing top of the line customer service and a beautiful end product.
2.Interactive project portalOur construction management software provides real-time 24/7 access to construction scheduling, change orders, documents, photos, warranty management, selections, and much more. It will allow you to see your project progress on a daily basis from anywhere in the world (yes, you can still take that trip to Japan you were planning on!) Plus, everything can be managed in one place and the app can be accessed on all devices.
3.Dedicated remodeling project developerNo more one-man show. A builder that runs between several projects while trying to manage his own company at the same time? Thats not anyones ideal situation. Your dedicated project developer is in charge of one thing only, to communicate with you. During the pre-construction stage and throughout the entire design process, we will make sure that we build your home exactly to the specifications that your talented architect or designer envisioned and planned.
4.Dedicated remodeling project managerYour project manager will visit your home daily and update your project portal with photos and important updates. This individual will manage the talented Joseph & Berry carpenters and trade partners to attain the best project results possible.
Learn more how we can help you LOVE your home again
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Joseph & Berry: Luxury Home Remodeling Dallas, Kitchen & Bathroom
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Recent Job Requests for Additions & Remodeling Contractors in Dallas, TX
Project: Remodel a Bathroom
Date: 10/01/2019
Extensiveness of Remodel: I plan to maintain existing bathroom floorplan
Shower / Bath: No - I will keep the existing shower or bath as is
Toilet: No - I will keep the existing toilet as is
Cabinets / Vanity: Yes - I plan to update the cabinets / vanity
Countertops: Yes - I plan to update the countertops
Sinks: Yes - I plan to update the sinks
Flooring: Yes - I plan to update the flooring
Request Stage: Planning & Budgeting
Desired Completion Date: Less than 2 months
Property Owner: Yes
Requires Work on Historical Structure: No
Covered by Insurance: No
Request for Commercial Location: No
Project: Renovate or Repair a Home
Date: 10/01/2019
Project Description: Several repair projects of varying nature
Project: Remodel a Bathroom
Date: 10/01/2019
Extensiveness of Remodel: I am considering changes to bathroom floorplan
Shower / Bath: Yes - I want to move or install a new shower or bath
Toilet: Yes - I will be replacing or moving the toilet
Cabinets / Vanity: Yes - I plan to update the cabinets / vanity
Countertops: Yes - I plan to update the countertops
Sinks: Yes - I plan to update the sinks
Flooring: Yes - I plan to update the flooring
Request Stage: Planning & Budgeting
Desired Completion Date: More than 2 months
Comment: I needs to be totally gutted from floor to ceiling.
Project: Remodel a Bathroom
Date: 10/01/2019
Extensiveness of Remodel: I am considering changes to bathroom floorplan
Shower / Bath: Yes - I want to move or install a new shower or bath
Toilet: Yes - I will be replacing or moving the toilet
Cabinets / Vanity: Yes - I plan to update the cabinets / vanity
Countertops: Yes - I plan to update the countertops
Sinks: Yes - I plan to update the sinks
Flooring: Yes - I plan to update the flooring
Request Stage: Planning & Budgeting
Desired Completion Date: More than 2 months
Comment: Need estimate for updating house by remodeling kitchen, bathroom, redoing hardwood floors, bringing electrical and plumbing to code. Estimate for bathrooms and electrical and plumbing needed NOW!
Project: Renovate or Repair a Home
Date: 10/01/2019
Project Description: Major home repair project
Project Type: Interior
Work included: Other
Request Stage: Ready to Hire
Desired Completion Date: Timing is flexible
What kind of location is this?: Home/Residence
Historical Work: No
Property Owner: Yes
Comment: The floor in main hallway is sinking; support beam not properly installed when house was built. I have a pier & beam foundation.
Project: Build an Addition
Date: 10/01/2019
Project Description: Design and build
Request Stage: Planning & Budgeting
Desired Completion Date: Timing is flexible
Project: Remodel a Bathroom
Date: 10/01/2019
Extensiveness of Remodel: I plan to maintain existing bathroom floorplan
Shower / Bath: No - I will keep the existing shower or bath as is
Toilet: No - I will keep the existing toilet as is
Cabinets / Vanity: Yes - I plan to update the cabinets / vanity
Countertops: Yes - I plan to update the countertops
Sinks: Yes - I plan to update the sinks
Flooring: Yes - I plan to update the flooring
Request Stage: Planning & Budgeting
Desired Completion Date: Timing is flexible
Property Owner: Yes
Requires Work on Historical Structure: No
Covered by Insurance: No
Request for Commercial Location: No
Project: Remodel or Renovate One or More Rooms
Date: 10/01/2019
Nature of project: Remodel / update the entire home
Rooms to be Remodeled: Kitchen, Bathroom(s), Bedroom(s), Garage
Request Stage: Ready to Hire
Desired Completion Date: Less than 2 months
What kind of location is this?: Home/Residence
Comment: house neeed fix
Project: Remodel a Bathroom
Date: 09/2019
Extensiveness of Remodel: I plan to maintain existing bathroom floorplan
Shower / Bath: Yes - I want to move or install a new shower or bath
Toilet: Yes - I will be replacing or moving the toilet
Cabinets / Vanity: Yes - I plan to update the cabinets / vanity
Countertops: No - I do not plan to update the countertops
Sinks: No - I do not plan to update the sinks
Flooring: No - I do not plan to update the flooring
Request Stage: Ready to Hire
Desired Completion Date: Less than 2 months
Property Owner: Yes
Requires Work on Historical Structure: No
Covered by Insurance: No
Request for Commercial Location: No
Comment: This house was built in the 1947 it was use as the office of the neighborhood so therefore, the bathroom is small. I am wanting to replace the tub, toilet and replacing the sink and cabinets with a paddle Stool sink. I will be purchasing all materials that is needed. Im hoping to find someone that can give me an affordable price for labor only.
Project: Remodel a Bathroom
Date: 09/2019
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25 Best Remodeling Contractors - Dallas TX | Home Additions
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Learn designer tricks for creating a welcoming desert oasis, including using cool, light-toned materials. Native plants thrive in their natural environment while adding color and texture to the outdoor living areas.
Tour this Newport Beach home designed by Blackband Design with a rustic, coastal aesthetic.
This newly constructed Phoenix home, designed by The Ranch Mine, embraces the outdoors and uses the cool desert night air to help with added ventilation.
Designer Kenna Stout transformed this home into a vibrant midcentury space perfect for entertaining.
Join Blackband Design as they give you a tour this Newport Beach, CA, home where Hollywood glam meets 70s funk.
Join the designers from Cloth & Kind as they give you a home tour through this modern-day farmhouse, that truly stands out among the rest.
This Atlanta townhome is inspired by the industrial style of urban buildings.
Architect Tom Ward gives a tour of a home he designed in Jackson, WY.
Tour designer Ili Hidalgo-Nilsson's beautiful Atlanta townhome.
This 1980s home in Phoenix boasts a modern redesign with shade and privacy.
Architect Jerry Locati tours a home he designed in Bozeman, MT.
Robert Nebolon gives a tour of a home he designed in Knoxville, Tennessee.
Brian Patrick Flynn shows a small, sustainable farmhouse in Serenbe, GA.
The Sol House in Phoenix is designed for cool living in the desert heat.
Montana architect Jerry Locati explains the evolution of Western design.
The 2016 HGTV Ultimate Outdoor Awards winner shares his design process.
Caitlin McCarthy shares what inspires her to create interior design.
Brian Patrick Flynn gives this kitchen a high-end look on a small budget.
Brian Patrick Flynn's basement design is light-filled and family-friendly.
Brian Patrick Flynn shows a small, sustainable farmhouse in Serenbe, GA.
Organization is the key to Brian Patrick Flynn's efficient mudroom design.
Brian Patrick Flynn shows how he used neutrals in a baby boy's nursery.
Brian Patrick Flynn's master suite design was inspired by menswear fabrics.
Brian Patrick Flynn creates a cool, casual dining room with saturated hues.
Brian Patrick Flynn gives a kitchen a modern, feminie French Country redo.
Teal tones help Brian Patrick Flynn add a nautical vibe to a boy's bedroom.
Brian Patrick Flynn uses flea-market finds to update a kitchen on a budget.
Brian Patrick Flynn's spacious basement design won't break the budget.
Brian Patrick Flynn styled this guest room as a multipurpose family space.
Silver fixtures accent Brian Patrick Flynn's black-and-white bathroom.
Brian Patrick Flynn shares ideas for designing a pet-friendly family room.
See how Brian Patrick Flynn gave this walk-in closet a ton of wow factor.
Brian Patrick Flynn uses texture and neutrals in an out-of-the-box bedroom.
See how Brian Patrick Flynn made a rental property his own on a budget.
Brian Patrick Flynn shares tips on choosing colors for a dark bedroom.
Check out how Brian Patrick Flynn renovated his own outdoor living space.
Brian Patrick Flynn transforms a huge attic space into a cheery boy's room.
Brian Patrick Flynn uses color to create a cozy cottage-style girl's room.
Brian Patrick Flynn uses creative decorating to design a stylish and functional entryway.
See how Brian Patrick Flynn creates a 'big space' feel in a small bathroom.
Brian Patrick Flynn's front porch design honors the home's Craftsman style.
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Remodeling Ideas, Home Planning, Kitchen & Bath Design - hgtv.com
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Go to https://www.thumbtack.com/ today to find and hire skilled local professionals in your area. It's fast, easy, and free!
Today on Modern Builds I'm renovating / updating my old, ugly, small bathroom; all for under $500! This was my first remodel - type project and I'm really happy with how it came out. I was pretty heavily influenced by the modern, contemporary farmhouse style of Chip and Joanna Gaines from Fixer Upper.
LED Mirror Video: https://youtu.be/K88W6HweESw
MATERIALS AND SUPPLIES:___________________________________________________Sinks and Faucets:http://amzn.to/2t0mJi4Cabinet Handles: http://amzn.to/2u5m2sOCabinet Hinges:http://amzn.to/2t0rLegShelf Brackets:http://amzn.to/2tZ24iyShower S-Pipe:http://amzn.to/2u4RhEdShower Head:http://amzn.to/2u5px2oShower Rod:http://amzn.to/2tZhqDNShower Curtain:http://amzn.to/2u5bDwZShower Hooks:http://amzn.to/2tW7082Bathroom Accessory Set:http://amzn.to/2tZgPBJMinwax Provincial Stain:http://amzn.to/2tuHm9CDanish Oil:http://amzn.to/2sT5dRmCaulk:http://amzn.to/2sCvxvcLiquid Nails:http://amzn.to/2sCSfTZPine 1x6's (For Wall and Shelfs)Countertops: (Discontinued From Ikea)
Written article:http://www.modernbuilds.com/bathroom-...___DONT FORGET TO LIKE COMMENT AND SUBSCRIBE.Subscribe: https://goo.gl/pgDSS8___ADD ME ON:Instagram: https://goo.gl/UgEpJs | @modernbuildsFacebook: https://goo.gl/KiI1cXSubscribe: https://goo.gl/pgDSS8Website: http://www.modernbuilds.com/___Thanks for watching! -Mike MontgomeryMODERN BUILDShttp://www.modernbuilds.com/
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Remodeling a bathroom for Under $500 | DIY | How To | Modern Builds | EP. 67
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Bone remodeling, continuing process of synthesis and destruction that gives bone its mature structure and maintains normal calcium levels in the body. Destruction, or resorption, of bone by large cells called osteoclasts releases calcium into the bloodstream to meet the bodys metabolic needs and simultaneously allows the bonewhich is inhibited by its inorganic component from growing by cell division like other tissuesto alter size and shape as it grows to adult proportions. While the osteoclasts resorb bone at various sites, other cells called osteoblasts make new bone to maintain the skeletal structure. During childhood, bone formation outpaces destruction as growth proceeds. After skeletal maturity is reached, the two processes maintain an approximate balance.
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bone: Remodeling, growth, and development
Whereas renewal in tissues such as muscle occurs largely at a molecular level, renewal of bone occurs at a tissue level and is similar to
Osteoclasts act on the inner surfaces of bones, in the marrow cavity and the spaces of cancellous bone, to widen these cavities; they also act on the outer surfaces to reduce bony processes, such as the epiphyseal swellings at the ends of the long bones of the arm and leg. Osteoclast activity takes place behind the epiphyseal growth zone to reduce former swellings to the width of the lengthening shaft. Within the bone, osteoclastic destruction helps to convert immature bone (called woven bone) into mature compact bone (lamellar bone) by clearing long tubular spaces that will serve as centres for the development of osteons, the bony structures through which blood vessels pass.
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Bone remodeling | physiology | Britannica.com
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Kitchen Remodeling
Kitchen remodeling is the heart & art projectof 800 Remodeling. we understand just how important your kitchen remodeling process is, and how important it is to your home. were proud to provide quality work, exceptional customer service, and a devoted team of designers, builders, and installers to help turn your dcor ideas into reality. Kitchen Remodeling in Los Angeles Will increase your home value, and
your ROI will be averagely more than 100%! keep your kitchen updated with sophisticated cabinetry solutions that will answer your kitchen needs and preferences. For Over 40 Years of experience in Los Angeles, We offer free custom kitchen design upon any kitchen remodeling project with Los Angeles finest kitchen designers!
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Bathroom Remodeling
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Roofing
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General Contractor
Give Us To Try Any Job We Do It All Under One Roof!As the leading general contractor in Los Angeles, 800 Remodeling strives to deliver high-quality materials, a devoted team of skilled craftsmanship and exceptional customer service! We Handle all our remodeling jobs In-House and guarantee 100% customer satisfaction! 40 years of Experience comes in handy in Los Angeles general construction industry, and we will make sure that every project is completed the right way, no cutting corners and of course, always finish our projects on time and on budget.
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Room Addition / New Construction
The true art of remodeling houses lies in the ability to build new houses, new constructions, and room additions! at 800 Remodeling, we provide comprehensive Complete remodeling services and a variety of room additions options! When you build your new house, you get to choose every little aspect of your home. where the kitchen will be, how many rooms you want to build and how big each one will be. you get to design your interior space from scratch and customize it to your preferences and needs! At 800 Remodeling ensure you get nothing but the best, and we make sure youre 100% happy and satisfied with every blueprint, brick, and color we will add into your life.
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Exterior Remodeling
The way your house looks on the outside will reflect the life in the inside. no one to live in a house with color that peels off the walls, or a neglected backyard. Here at 800 Remodeling we provide the best exterior remodeling services in Los Angeles and offer any kind of exterior remodeling project you can think of. from Backyards and pools to outdoor kitchens and patio covers. Exterior remodeling will improve your house curb appeal, making it a more inviting house. We want your house to be the most beautiful in your neighborhood, and functional for you and for your family.
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Interior Remodeling
Your Interior space is the space you and your family living in. It is highly important to keep the interior of your home updated, sleek, and aesthetically pleasing. We have more than 40 years of experience remodeling interior spaces in Los Angeles Area and we would love the opportunity to design and build the house of your dreams. With cutting edge technology and 3D visualization, you can literally see your new home coming to life. We offer any kind of interior remodeling project you can think off, from painting your interior walls, install new windows, re-build your in-house stairs and professional mold inspection!
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800 Remodeling Inc., | Family-Owned Construction Company In LA
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Ventricular remodeling – Wikipedia -
September 29, 2019 by
Mr HomeBuilder
In cardiology, ventricular remodeling (or cardiac remodeling)[1] refers to changes in the size, shape, structure, and function of the heart. This can happen as a result of exercise (physiological remodeling) or after injury to the heart muscle (pathological remodeling).[2] The injury is typically due to acute myocardial infarction (usually transmural or ST segment elevation infarction), but may be from a number of causes that result in increased pressure or volume, causing pressure overload or volume overload (forms of strain) on the heart. Chronic hypertension, congenital heart disease with intracardiac shunting, and valvular heart disease may also lead to remodeling. After the insult occurs, a series of histopathological and structural changes occur in the left ventricular myocardium that lead to progressive decline in left ventricular performance. Ultimately, ventricular remodeling may result in diminished contractile (systolic) function and reduced stroke volume.
Physiological remodeling is reversible while pathological remodeling is mostly irreversible. Remodeling of the ventricles under left/right pressure demand make mismatches inevitable. Pathologic pressure mismatches between the pulmonary and systemic circulation guide compensatory remodeling of the left and right ventricles. The term "reverse remodeling" in cardiology implies an improvement in ventricular mechanics and function following a remote injury or pathological process.[3][4][5]
Ventricular remodeling may include ventricular hypertrophy, ventricular dilation, cardiomegaly, and other changes. It is an aspect of cardiomyopathy, of which there are many types. Concentric hypertrophy is due to pressure overload, while eccentric hypertrophy is due to volume overload.[6]
The cardiac myocyte is the major cell involved in remodeling. Fibroblasts, collagen, the interstitium, and the coronary vessels to a lesser extent, also play a role. A common scenario for remodeling is after myocardial infarction. There is myocardial necrosis (cell death) and disproportionate thinning of the heart. This thin, weakened area is unable to withstand the pressure and volume load on the heart in the same manner as the other healthy tissue. As a result, there is dilatation of the chamber arising from the infarct region. The initial remodeling phase after a myocardial infarction results in repair of the necrotic area and myocardial scarring that may, to some extent, be considered beneficial since there is an improvement in or maintenance of LV function and cardiac output. Over time, however, as the heart undergoes ongoing remodeling, it becomes less elliptical and more spherical. Ventricular mass and volume increase, which together adversely affect cardiac function. Eventually, diastolic function, or the heart's ability to relax between contractions may become impaired, further causing decline.[7]
After a myocardial infarction (MI), cardiac myocyte death can be triggered by necrosis, apoptosis, or autophagy, leading to thinning of the cardiac wall.[8] The surviving cardiac myocytes either arrange in parallel or in series to each other, contributing to ventricular dilatation or ventricular hypertrophy, depending on the loading stress on the ventricular wall.[7] Besides, reduced expression of V1 mysoin and L-type calcium channels on cardiac myocytes are also thought to cause cardiac remodelling. Under normal body conditions, fatty acid accounts for 60 to 90% of the energy supply of the heart. Post MI, as fatty acid oxidation decreases, it leads to reduced energy supply for the cardiac myocytes, accumulation of fatty acids to toxic levels, and dysfunction of mitochondria. These consequences also led to the increase in oxidative stress on the heart, causing the proliferation of fibroblasts, activation of metalloproteinases, and induction of apoptosis, which would be explained below. Besides, inflammatory immune response after MI also contributes to the above changes.[8]
Besides, the cardiac interstitium which consisted of largely Type I and Type III collagen fibres are also involved in cardiac remodeling. Cardiac collagen is synthesized by fibroblasts and degraded by metalloproteinases.[7] Fibroblasts are activated post MI, leading to increased collagen synthesis and fibrosis of the heart.[8] Increase expression of MMP1 and MMP9 led to degradation of collagen fibres, and subsequently dilatation of the heart.[7] Several signal pathways such as Angiotensin II, Transforming growth factor beta (TGF-beta), and Endothelin 1 are known to trigger synthesis and degradation of collagen fibres in the heart.[8]
Other factors such as high blood pressure, activation of sympathetic system which releases norepinephrine, activation of reninangiotensin system which releases renin and anti-diuretic hormones are important contributors of cardiac remodelling. However, atrial natriuretic peptide is thought to be cardio-protective.[7]
Remodeling of the heart is evaluated by performing an echocardiogram. The size and function of the atria and ventricles can be characterized using this test.
Many factors influence the time course and extent of remodeling, including the severity of the injury, secondary events (recurrent ischemia or infarction), neurohormonal activation, genetic factors and gene expression, and treatment. Medications may attenuate remodeling. Angiotensin-converting enzyme (ACE) inhibitors have been consistently shown to decrease remodeling in animal models or transmural infarction and chronic pressure overload. Clinical trials have shown that ACE inhibitor therapy after myocardial infarction leads to improved myocardial performance, improved ejection fraction, and decreased mortality compared to patients treated with placebo. Likewise, inhibition of aldosterone, either directly or indirectly, leads to improvement in remodeling.[9] Carvedilol, a 3rd generation beta blocker, may actually reverse the remodeling process by reducing left ventricular volumes and improving systolic function.[10][11] Early correction of congenital heart defects, if appropriate, may prevent remodeling, as will treatment of chronic hypertension or valvular heart disease. Often, reverse remodeling, or improvement in left ventricular function, will also be seen.[citation needed]
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Ventricular remodeling - Wikipedia
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Kitchen Designs by Ken Kellys focus is on DESIGN, and this is what sets us apart when creatingbeautiful kitchens. Our design process is intentional and customized to your specific needs, your desired aesthetic, and the architectural integrity of your home. Our design team has created some of the most beautiful custom kitchens onLong Island and in the NY metro area that aretrendsetting inthe industry. Our owners, Ken and Grace, sit on industrydesign councils and travel throughout America and Europe finding the best products andtechnology available on the market. When browsing the project gallery, please note that large kitchens are easier to photograph; althoughwe do high-end custom kitchensfor those whohave that kind of budget,our specialty and expertise truly helps those on abudget as well. It gives us tremendous pleasure knowing that we can give youthe highest quality possible and the best design for your investmentno matter how large or small of a project.Enjoy the kitchen design gallery. If you prefer to flip through photos only, scroll down to the photos only section.
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Kitchens Remodel & Designs | Long Island | New York City
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